Solvent for etomidate may cause pain and adverse effects

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Solvent for etomidate may cause pain and adverse effects.

We tested the hypothesis that the solvent for etomidate was a factor in the incidence of pain and other side effects after injection, and that these were associated with histamine release. Nine of 10 volunteers who received etomidate in a propylene glycol formulation reported moderate to severe pain on injection; only one of 10 subjects who received a lipid emulsion formulation reported mild pa...

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Etomidate and injection pain in children.

Editor—We read with interest the study by Nyman and colleagues 1 concerning etomidate and injection pain in children. It is well accepted that a single bolus dose of eto-midate can result in adrenal suppression in adult patients, not only the critically ill 2 but also in healthy young adults. 3 Single bolus dose etomidate has also been linked with impaired adrenal function in critically ill chi...

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Review: cannabinoids and codeine have similar effects on pain relief, but cannabinoids commonly cause adverse psychotropic effects.

D a t a s o u r c e s Full publications of studies were identified by searching MEDLINE (1966 to 1999), EMBASE/Excerpta Medica (1974 to 1999), the Oxford Pain Database (1950 to 1994), and the Cochrane Library (1999, Issue 3) with the terms marijuana, marihuana, mariuana, cannabis, cannabinoids, tetrahydrocannabinol (THC), delta-9-THC, nabilone, pain, analgesia, and random. Bibliographies of rel...

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Respiratory effects of etomidate.

The respiratory effects of etomidate 0.3 mg/kg were studied in patients premedicated with either diazepam and atropine or papaveretum and hyoscine. The incidence of apnoea was 40% in those who received the non-narcotic premedication, compared with 27% in those who received the opiate. Those premedicated with diazepam and atropine showed a significant increase in respiratory frequency which was ...

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Relationship between Hypnosis for Pain Management in Labor and Adverse Neonatal Outcomes: A Systematic Review

Background: Many techniques have been proposed to relieve labor pain, one of which is hypnotherapy, which can be defined as the usage of hypnosis during labor to alleviate pain or anxiety. The aim of this systematic review was to examine the possible relationship between hypnosis and neonatal outcomes based on the available reports. Methods: Major databases, including PubMed, Web of Science, S...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1999

ISSN: 0007-0912

DOI: 10.1093/bja/83.3.464